Tophi (plural for tophus) are accumulations of uric acid crystals that form visible lumps in and around joints, tendons, and other connective tissues. Also referred to as gout nodules, these deposits result from elevated levels of uric acid.

What is the difference between gout and tophi?

The difference between gout and tophi is; gout causes joint pain and inflammation, where tophi are physical manifestations of long-term, uncontrolled gout. For people with chronic gout, tophi develop due to excess uric acid remaining in the blood. Small bumps at a joint may be visible as soon as a few weeks depending on the individual. If left untreated, tophi can become permanent, cause joint deformaties, and limit range of motion.

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