NSAIDs, or Nonsteroidal Anti-Inflammatory Drugs, are medications commonly used to reduce pain, inflammation, and fever. They work by blocking enzymes called COX-1 and COX-2, which play a role in producing substances that contribute to inflammation and pain.

The top five NSAIDs are: ibuprofen (Advil, Motrin), naproxen (Aleve), aspirin (Bayer), diclofenac (Voltaren), and indomethacin (Indocin).

For gout, healthcare professionals often recommend NSAIDs such as indomethacin, naproxen, or ibuprofen to alleviate inflammation and discomfort. These medications temporarily help reduce some pain and swelling from a full blown gout attack.

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