Pegloticase (brand name Krystexxa) is a medication designed to treat severe chronic gout. Administered intravenously, it converts uric acid into a form that can be easily filtered by the kidneys; reducing the accumulation of uric acid crystals in the joints.

Is Pegloticase (Krystexxa) better than allopurinol?

Pegloticase and allopurinol are both medications used to manage gout, but they function differently. Allopurinol is an oral medication that limits the production of uric acid. An injection of pegloticase is typically reserved for extreme cases of gout, when other medications like allopurinol have been ineffective.

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