Febuxostat, marketed as Uloric, is a medication prescribed to treat gout. Taken orally, this drug acts by inhibiting xanthine oxidase, an enzyme involved in the production of uric acid. It is often prescribed for individuals who cannot tolerate or do not respond well to other gout medications.
Which is better allopurinol or febuxostat for gout?
Both medications ultimately aim to regulate xanthine oxidase, but they act through different pathways. Allopurinol does so through competitive inhibition after metabolic conversion, whereas febuxostat directly blocks xanthine oxidase without the need for metabolic activation.
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